Acyclovir vs Diphenhydramine

## Acyclovir vs Diphenhydramine: Overview

This comparison examines the pharmacological differences between **Acyclovir** and **Diphenhydramine**.

## Mechanism of Action

**Acyclovir**: Guanosine analogue inhibiting viral DNA polymerase.

**Diphenhydramine**: First-generation H1 antihistamine with anticholinergic properties.

## Pharmacokinetics

**Half-life**: Acyclovir — 2.5-3.3 hours; Diphenhydramine — 2-8 hours.

## Chemical Properties

**Molecular Formula**: Acyclovir — C8H11N5O3; Diphenhydramine — C17H21NO.

**Molecular Weight**: Acyclovir — 225.2050 g/mol; Diphenhydramine — 255.3550 g/mol.

**Type**: Acyclovir — Small molecule; Diphenhydramine — Small molecule.