Amlodipine vs Tofacitinib

## Amlodipine vs Tofacitinib: Overview

This comparison examines the pharmacological differences between **Amlodipine** and **Tofacitinib**.

## Mechanism of Action

**Amlodipine**: Dihydropyridine calcium channel blocker.

**Tofacitinib**: Pan-JAK inhibitor with preference for JAK1 and JAK3 blocking pro-inflammatory cytokine signaling.

## Pharmacokinetics

**Half-life**: Amlodipine — 30-50 hours; Tofacitinib — 3.2 hours.

## Chemical Properties

**Molecular Formula**: Amlodipine — C20H25ClN2O5; Tofacitinib — C16H20N6O.

**Molecular Weight**: Amlodipine — 408.8800 g/mol; Tofacitinib — 312.3700 g/mol.

**Type**: Amlodipine — Small molecule; Tofacitinib — Small molecule.