Bisoprolol vs Captopril

## Bisoprolol vs Captopril: Overview

This comparison examines the pharmacological differences between **Bisoprolol** and **Captopril**.

## Mechanism of Action

**Bisoprolol**: Highly selective beta-1 adrenergic receptor blocker reducing heart rate and myocardial contractility.

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

## Pharmacokinetics

**Half-life**: Bisoprolol — 10-12 hours; Captopril — 1.9 hours.

## Chemical Properties

**Molecular Formula**: Bisoprolol — C18H31NO4; Captopril — C9H15NO3S.

**Molecular Weight**: Bisoprolol — 325.4470 g/mol; Captopril — 217.2850 g/mol.

**Type**: Bisoprolol — Small molecule; Captopril — Small molecule.