Captopril vs Digoxin

## Captopril vs Digoxin: Overview

This comparison examines the pharmacological differences between **Captopril** and **Digoxin**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Digoxin**: Inhibits Na+/K+-ATPase, increasing intracellular calcium.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Digoxin — 36-48 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Digoxin — C41H64O14.

**Molecular Weight**: Captopril — 217.2850 g/mol; Digoxin — 780.9430 g/mol.

**Type**: Captopril — Small molecule; Digoxin — Small molecule.