Captopril vs Fluconazole

## Captopril vs Fluconazole: Overview

This comparison examines the pharmacological differences between **Captopril** and **Fluconazole**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Fluconazole**: Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase).

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Fluconazole — 30 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Fluconazole — C13H12F2N6O.

**Molecular Weight**: Captopril — 217.2850 g/mol; Fluconazole — 306.2710 g/mol.

**Type**: Captopril — Small molecule; Fluconazole — Small molecule.