Captopril vs Lorazepam

## Captopril vs Lorazepam: Overview

This comparison examines the pharmacological differences between **Captopril** and **Lorazepam**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Lorazepam**: Intermediate-acting benzodiazepine enhancing GABA-A receptor chloride conductance.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Lorazepam — 10-20 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Lorazepam — C15H10Cl2N2O2.

**Molecular Weight**: Captopril — 217.2850 g/mol; Lorazepam — 321.1580 g/mol.

**Type**: Captopril — Small molecule; Lorazepam — Small molecule.