Captopril vs Phenytoin

## Captopril vs Phenytoin: Overview

This comparison examines the pharmacological differences between **Captopril** and **Phenytoin**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Phenytoin**: Sodium channel blocker stabilizing inactive state.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Phenytoin — 22 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Phenytoin — C15H12N2O2.

**Molecular Weight**: Captopril — 217.2850 g/mol; Phenytoin — 252.2680 g/mol.

**Type**: Captopril — Small molecule; Phenytoin — Small molecule.