Same Indication

Citalopram vs Diphenhydramine

## Citalopram vs Diphenhydramine: Overview

This comparison examines the pharmacological differences between **Citalopram** and **Diphenhydramine**.

## Mechanism of Action

**Citalopram**: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

**Diphenhydramine**: First-generation H1 antihistamine with anticholinergic properties.

## Pharmacokinetics

**Half-life**: Citalopram — 35 hours; Diphenhydramine — 2-8 hours.

## Chemical Properties

**Molecular Formula**: Citalopram — C20H21FN2O; Diphenhydramine — C17H21NO.

**Molecular Weight**: Citalopram — 324.3920 g/mol; Diphenhydramine — 255.3550 g/mol.

**Type**: Citalopram — Small molecule; Diphenhydramine — Small molecule.