Cyclosporine vs Sildenafil

## Cyclosporine vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Cyclosporine** and **Sildenafil**.

## Mechanism of Action

**Cyclosporine**: Calcineurin inhibitor suppressing T-cell activation.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Cyclosporine — 6-12 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Cyclosporine — C62H111N11O12; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Cyclosporine — 1202.6100 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Cyclosporine — Protein; Sildenafil — Small molecule.