Cyclosporine vs Sitagliptin

## Cyclosporine vs Sitagliptin: Overview

This comparison examines the pharmacological differences between **Cyclosporine** and **Sitagliptin**.

## Mechanism of Action

**Cyclosporine**: Calcineurin inhibitor suppressing T-cell activation.

**Sitagliptin**: DPP-4 inhibitor increasing incretin levels.

## Pharmacokinetics

**Half-life**: Cyclosporine — 6-12 hours; Sitagliptin — 12.4 hours.

## Chemical Properties

**Molecular Formula**: Cyclosporine — C62H111N11O12; Sitagliptin — C16H15F6N5O.

**Molecular Weight**: Cyclosporine — 1202.6100 g/mol; Sitagliptin — 407.3140 g/mol.

**Type**: Cyclosporine — Protein; Sitagliptin — Small molecule.