Dapagliflozin vs Sildenafil

## Dapagliflozin vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Dapagliflozin** and **Sildenafil**.

## Mechanism of Action

**Dapagliflozin**: Selective SGLT2 inhibitor reducing renal glucose and sodium reabsorption.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Dapagliflozin — 12.9 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Dapagliflozin — C21H25ClO6; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Dapagliflozin — 408.8730 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Dapagliflozin — Small molecule; Sildenafil — Small molecule.