Dexamethasone vs Methotrexate

## Dexamethasone vs Methotrexate: Overview

This comparison examines the pharmacological differences between **Dexamethasone** and **Methotrexate**.

## Mechanism of Action

**Dexamethasone**: Potent synthetic glucocorticoid.

**Methotrexate**: Dihydrofolate reductase inhibitor.

## Pharmacokinetics

**Half-life**: Dexamethasone — 36-54 hours; Methotrexate — 3-10 hours.

## Chemical Properties

**Molecular Formula**: Dexamethasone — C22H29FO5; Methotrexate — C20H22N8O5.

**Molecular Weight**: Dexamethasone — 392.4610 g/mol; Methotrexate — 454.4400 g/mol.

**Type**: Dexamethasone — Small molecule; Methotrexate — Small molecule.