Diltiazem vs Sildenafil

## Diltiazem vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Diltiazem** and **Sildenafil**.

## Mechanism of Action

**Diltiazem**: Benzothiazepine calcium channel blocker.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Diltiazem — 3-4.5 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Diltiazem — C22H26N2O4S; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Diltiazem — 414.5190 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Diltiazem — Small molecule; Sildenafil — Small molecule.