Doxycycline vs Hydroxychloroquine

## Doxycycline vs Hydroxychloroquine: Overview

This comparison examines the pharmacological differences between **Doxycycline** and **Hydroxychloroquine**.

## Mechanism of Action

**Doxycycline**: Inhibits bacterial protein synthesis by binding 30S ribosomal subunit.

**Hydroxychloroquine**: Accumulates in lysosomes raising pH; inhibits toll-like receptor signaling.

## Pharmacokinetics

**Half-life**: Doxycycline — 18-22 hours; Hydroxychloroquine — 40-50 days.

## Chemical Properties

**Molecular Formula**: Doxycycline — C22H24N2O8; Hydroxychloroquine — C18H26ClN3O.

**Molecular Weight**: Doxycycline — 444.4350 g/mol; Hydroxychloroquine — 335.8720 g/mol.

**Type**: Doxycycline — Small molecule; Hydroxychloroquine — Small molecule.