Durvalumab vs Fluconazole

## Durvalumab vs Fluconazole: Overview

This comparison examines the pharmacological differences between **Durvalumab** and **Fluconazole**.

## Mechanism of Action

**Durvalumab**: Human IgG1 kappa anti-PD-L1 monoclonal antibody blocking PD-L1 binding to PD-1 and CD80.

**Fluconazole**: Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase).

## Pharmacokinetics

**Half-life**: Durvalumab — 17 days; Fluconazole — 30 hours.

## Chemical Properties

**Molecular Formula**: Durvalumab — N/A; Fluconazole — C13H12F2N6O.

**Molecular Weight**: Durvalumab — N/A; Fluconazole — 306.2710 g/mol.

**Type**: Durvalumab — Antibody; Fluconazole — Small molecule.