Erlotinib vs Tamoxifen

## Erlotinib vs Tamoxifen: Overview

This comparison examines the pharmacological differences between **Erlotinib** and **Tamoxifen**.

## Mechanism of Action

**Erlotinib**: Reversible inhibitor of EGFR (HER1) tyrosine kinase, blocking autophosphorylation.

**Tamoxifen**: Selective estrogen receptor modulator (SERM).

## Pharmacokinetics

**Half-life**: Erlotinib — 36 hours; Tamoxifen — 5-7 days.

## Chemical Properties

**Molecular Formula**: Erlotinib — C22H23N3O4; Tamoxifen — C26H29NO.

**Molecular Weight**: Erlotinib — 393.4380 g/mol; Tamoxifen — 371.5150 g/mol.

**Type**: Erlotinib — Small molecule; Tamoxifen — Small molecule.