Esomeprazole vs Omeprazole

## Esomeprazole vs Omeprazole: Overview

This comparison examines the pharmacological differences between **Esomeprazole** and **Omeprazole**.

## Mechanism of Action

**Esomeprazole**: S-isomer of omeprazole; proton pump inhibitor irreversibly blocking gastric H+/K+-ATPase.

**Omeprazole**: Proton pump inhibitor that irreversibly blocks H+/K+-ATPase.

## Pharmacokinetics

**Half-life**: Esomeprazole — 1-1.5 hours; Omeprazole — 0.5-1 hour.

## Chemical Properties

**Molecular Formula**: Esomeprazole — C17H19N3O3S; Omeprazole — C17H19N3O3S.

**Molecular Weight**: Esomeprazole — 345.4170 g/mol; Omeprazole — 345.4170 g/mol.

**Type**: Esomeprazole — Small molecule; Omeprazole — Small molecule.