Furosemide vs Tofacitinib

## Furosemide vs Tofacitinib: Overview

This comparison examines the pharmacological differences between **Furosemide** and **Tofacitinib**.

## Mechanism of Action

**Furosemide**: Loop diuretic inhibiting Na-K-2Cl cotransporter.

**Tofacitinib**: Pan-JAK inhibitor with preference for JAK1 and JAK3 blocking pro-inflammatory cytokine signaling.

## Pharmacokinetics

**Half-life**: Furosemide — 2 hours; Tofacitinib — 3.2 hours.

## Chemical Properties

**Molecular Formula**: Furosemide — C12H11ClN2O5S; Tofacitinib — C16H20N6O.

**Molecular Weight**: Furosemide — 330.7440 g/mol; Tofacitinib — 312.3700 g/mol.

**Type**: Furosemide — Small molecule; Tofacitinib — Small molecule.