Hydrochlorothiazide vs Tolbutamide

## Hydrochlorothiazide vs Tolbutamide: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Tolbutamide**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Tolbutamide — N/A.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Tolbutamide — N/A.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Tolbutamide — N/A.

**Type**: Hydrochlorothiazide — Small molecule; Tolbutamide — Small molecule.