Hydromorphone vs Morphine

## Hydromorphone vs Morphine: Overview

This comparison examines the pharmacological differences between **Hydromorphone** and **Morphine**.

## Mechanism of Action

**Hydromorphone**: Semisynthetic mu-opioid receptor agonist approximately 5 times more potent than morphine.

**Morphine**: Mu-opioid receptor agonist.

## Pharmacokinetics

**Half-life**: Hydromorphone — 2-3 hours; Morphine — 2-3 hours.

## Chemical Properties

**Molecular Formula**: Hydromorphone — C17H19NO3; Morphine — C17H19NO3.

**Molecular Weight**: Hydromorphone — 285.3380 g/mol; Morphine — 285.3380 g/mol.

**Type**: Hydromorphone — Small molecule; Morphine — Small molecule.