Ibuprofen vs Sildenafil

## Ibuprofen vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Ibuprofen** and **Sildenafil**.

## Mechanism of Action

**Ibuprofen**: Non-selective COX inhibitor reducing prostaglandin synthesis.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Ibuprofen — 2-4 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Ibuprofen — C13H18O2; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Ibuprofen — 206.2810 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Ibuprofen — Small molecule; Sildenafil — Small molecule.