Ipilimumab vs Leflunomide

## Ipilimumab vs Leflunomide: Overview

This comparison examines the pharmacological differences between **Ipilimumab** and **Leflunomide**.

## Mechanism of Action

**Ipilimumab**: Fully human anti-CTLA-4 IgG1 monoclonal antibody that blocks CTLA-4 inhibitory signaling.

## Pharmacokinetics

**Half-life**: Ipilimumab — 14.7 days; Leflunomide — N/A.

## Chemical Properties

**Type**: Ipilimumab — Antibody; Leflunomide — Small molecule.