Ipilimumab vs Methylprednisolone

## Ipilimumab vs Methylprednisolone: Overview

This comparison examines the pharmacological differences between **Ipilimumab** and **Methylprednisolone**.

## Mechanism of Action

**Ipilimumab**: Fully human anti-CTLA-4 IgG1 monoclonal antibody that blocks CTLA-4 inhibitory signaling.

**Methylprednisolone**: Intermediate-acting synthetic glucocorticoid.

## Pharmacokinetics

**Half-life**: Ipilimumab — 14.7 days; Methylprednisolone — 18-36 hours.

## Chemical Properties

**Molecular Formula**: Ipilimumab — N/A; Methylprednisolone — C22H30O5.

**Molecular Weight**: Ipilimumab — N/A; Methylprednisolone — 374.4710 g/mol.

**Type**: Ipilimumab — Antibody; Methylprednisolone — Small molecule.