Lisinopril vs Spironolactone

## Lisinopril vs Spironolactone: Overview

This comparison examines the pharmacological differences between **Lisinopril** and **Spironolactone**.

## Mechanism of Action

**Lisinopril**: ACE inhibitor preventing conversion of angiotensin I to angiotensin II.

**Spironolactone**: Mineralocorticoid receptor antagonist.

## Pharmacokinetics

**Half-life**: Lisinopril — 12 hours; Spironolactone — 1.4 hours.

## Chemical Properties

**Molecular Formula**: Lisinopril — C21H31N3O5; Spironolactone — C24H32O4S.

**Molecular Weight**: Lisinopril — 405.4900 g/mol; Spironolactone — 416.5740 g/mol.

**Type**: Lisinopril — Small molecule; Spironolactone — Small molecule.