Loratadine vs Trimethoprim

## Loratadine vs Trimethoprim: Overview

This comparison examines the pharmacological differences between **Loratadine** and **Trimethoprim**.

## Mechanism of Action

**Loratadine**: Second-generation H1 antihistamine with minimal CNS effects.

**Trimethoprim**: Dihydrofolate reductase inhibitor (bacterial selective).

## Pharmacokinetics

**Half-life**: Loratadine — 8 hours; Trimethoprim — 8-10 hours.

## Chemical Properties

**Molecular Formula**: Loratadine — C22H23ClN2O2; Trimethoprim — C14H18N4O3.

**Molecular Weight**: Loratadine — 382.8800 g/mol; Trimethoprim — 290.3180 g/mol.

**Type**: Loratadine — Small molecule; Trimethoprim — Small molecule.