Loratadine vs Venlafaxine

## Loratadine vs Venlafaxine: Overview

This comparison examines the pharmacological differences between **Loratadine** and **Venlafaxine**.

## Mechanism of Action

**Loratadine**: Second-generation H1 antihistamine with minimal CNS effects.

**Venlafaxine**: Serotonin-norepinephrine reuptake inhibitor (SNRI).

## Pharmacokinetics

**Half-life**: Loratadine — 8 hours; Venlafaxine — 5 hours.

## Chemical Properties

**Molecular Formula**: Loratadine — C22H23ClN2O2; Venlafaxine — C17H27NO2.

**Molecular Weight**: Loratadine — 382.8800 g/mol; Venlafaxine — 277.4020 g/mol.

**Type**: Loratadine — Small molecule; Venlafaxine — Small molecule.