Lorazepam vs Paroxetine

## Lorazepam vs Paroxetine: Overview

This comparison examines the pharmacological differences between **Lorazepam** and **Paroxetine**.

## Mechanism of Action

**Lorazepam**: Intermediate-acting benzodiazepine enhancing GABA-A receptor chloride conductance.

**Paroxetine**: Potent selective serotonin reuptake inhibitor with additional muscarinic and NE reuptake inhibition.

## Pharmacokinetics

**Half-life**: Lorazepam — 10-20 hours; Paroxetine — 21 hours.

## Chemical Properties

**Molecular Formula**: Lorazepam — C15H10Cl2N2O2; Paroxetine — C19H20FNO3.

**Molecular Weight**: Lorazepam — 321.1580 g/mol; Paroxetine — 329.3730 g/mol.

**Type**: Lorazepam — Small molecule; Paroxetine — Small molecule.