Lorazepam vs Phenytoin

## Lorazepam vs Phenytoin: Overview

This comparison examines the pharmacological differences between **Lorazepam** and **Phenytoin**.

## Mechanism of Action

**Lorazepam**: Intermediate-acting benzodiazepine enhancing GABA-A receptor chloride conductance.

**Phenytoin**: Sodium channel blocker stabilizing inactive state.

## Pharmacokinetics

**Half-life**: Lorazepam — 10-20 hours; Phenytoin — 22 hours.

## Chemical Properties

**Molecular Formula**: Lorazepam — C15H10Cl2N2O2; Phenytoin — C15H12N2O2.

**Molecular Weight**: Lorazepam — 321.1580 g/mol; Phenytoin — 252.2680 g/mol.

**Type**: Lorazepam — Small molecule; Phenytoin — Small molecule.