Lovastatin vs Sildenafil

## Lovastatin vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Lovastatin** and **Sildenafil**.

## Mechanism of Action

**Lovastatin**: First naturally derived statin; prodrug hydrolyzed to active beta-hydroxy acid inhibiting HMG-CoA reductase.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Lovastatin — 2-3 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Lovastatin — C24H36O5; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Lovastatin — 404.5390 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Lovastatin — Small molecule; Sildenafil — Small molecule.