Metformin vs Rituximab

## Metformin vs Rituximab: Overview

This comparison examines the pharmacological differences between **Metformin** and **Rituximab**.

## Mechanism of Action

**Metformin**: Activates AMP-activated protein kinase, decreasing hepatic glucose production.

**Rituximab**: Chimeric anti-CD20 IgG1 monoclonal antibody inducing B-cell depletion via CDC, ADCC, and apoptosis.

## Pharmacokinetics

**Half-life**: Metformin — 4-9 hours; Rituximab — 22 days.

## Chemical Properties

**Molecular Formula**: Metformin — C4H11N5; Rituximab — N/A.

**Molecular Weight**: Metformin — 129.1640 g/mol; Rituximab — N/A.

**Type**: Metformin — Small molecule; Rituximab — Antibody.