Metformin vs Spironolactone

## Metformin vs Spironolactone: Overview

This comparison examines the pharmacological differences between **Metformin** and **Spironolactone**.

## Mechanism of Action

**Metformin**: Activates AMP-activated protein kinase, decreasing hepatic glucose production.

**Spironolactone**: Mineralocorticoid receptor antagonist.

## Pharmacokinetics

**Half-life**: Metformin — 4-9 hours; Spironolactone — 1.4 hours.

## Chemical Properties

**Molecular Formula**: Metformin — C4H11N5; Spironolactone — C24H32O4S.

**Molecular Weight**: Metformin — 129.1640 g/mol; Spironolactone — 416.5740 g/mol.

**Type**: Metformin — Small molecule; Spironolactone — Small molecule.