Phenytoin vs Valproic Acid

## Phenytoin vs Valproic Acid: Overview

This comparison examines the pharmacological differences between **Phenytoin** and **Valproic Acid**.

## Mechanism of Action

**Phenytoin**: Sodium channel blocker stabilizing inactive state.

**Valproic Acid**: Enhances GABA transmission and blocks sodium/calcium channels.

## Pharmacokinetics

**Half-life**: Phenytoin — 22 hours; Valproic Acid — 9-16 hours.

## Chemical Properties

**Molecular Formula**: Phenytoin — C15H12N2O2; Valproic Acid — C8H16O2.

**Molecular Weight**: Phenytoin — 252.2680 g/mol; Valproic Acid — 144.2110 g/mol.

**Type**: Phenytoin — Small molecule; Valproic Acid — Small molecule.