Pravastatin vs Tofacitinib

## Pravastatin vs Tofacitinib: Overview

This comparison examines the pharmacological differences between **Pravastatin** and **Tofacitinib**.

## Mechanism of Action

**Pravastatin**: Competitive inhibitor of HMG-CoA reductase.

**Tofacitinib**: Pan-JAK inhibitor with preference for JAK1 and JAK3 blocking pro-inflammatory cytokine signaling.

## Pharmacokinetics

**Half-life**: Pravastatin — 1.8 hours; Tofacitinib — 3.2 hours.

## Chemical Properties

**Molecular Formula**: Pravastatin — C23H36O7; Tofacitinib — C16H20N6O.

**Molecular Weight**: Pravastatin — 424.5280 g/mol; Tofacitinib — 312.3700 g/mol.

**Type**: Pravastatin — Small molecule; Tofacitinib — Small molecule.