Acebutolol

CHEMBL642 Phase 4 معتمد Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

336.4 g/mol

LogP

1.7

Phase

4

A beta-blocker that slows the heart rate and reduces the force of heartbeats by blocking the effects of adrenaline on the heart. It is used to treat high blood pressure and certain types of irregular heart rhythms, particularly fast heartbeats originating in the upper chambers of the heart. Patients should not stop taking it suddenly, as abrupt withdrawal can trigger rebound increases in heart rate and blood pressure.

الوزن الجزيئي

336,4000 g/mol

LogP

1,70

TPSA

87,70 Å²

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Hypertension Heart Failure Atrial Fibrillation Cardiovascular Disease

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

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SMILES

CCCC(=O)Nc1ccc(OCC(O)CNC(C)C)c(C(C)=O)c1

InChI

InChI=1S/C18H28N2O4/c1-5-6-18(23)20-14-7-8-17(16(9-14)13(4)21)24-11-15(22)10-19-12(2)3/h7-9,12,15,19,22H,5-6,10-11H2,1-4H3,(H,20,23)

Molecular Formula

C18H28N2O4

HBD / HBA

3 / 5

الروابط القابلة للدوران

10

الذرات الثقيلة

24

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

A beta-blocker that slows the heart rate and reduces the force of heartbeats by blocking the effects of adrenaline on the heart. It is used to treat high blood pressure and certain types of irregular heart rhythms, particularly fast heartbeats originating in the upper chambers of the heart. Patients should not stop taking it suddenly, as abrupt withdrawal can trigger rebound increases in heart rate and blood pressure.

Yes, Acebutolol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL642. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 1978. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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البنية

بيانات سريعة

الصيغة الجزيئية: C18H28N2O4
المرادفات: 1

روابط خارجية

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إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.