Amantadine Hydrochloride

CHEMBL1569 Phase 4 معتمد Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
187.7 g/mol
LogP
Phase
4

The hydrochloride salt form of amantadine, providing the same antiviral activity against influenza A and dopaminergic effects useful in Parkinson's disease and drug-induced movement disorders. This commonly used salt form is well-absorbed orally and excreted unchanged by the kidneys, requiring dose adjustment in patients with reduced kidney function.

الوزن الجزيئي

187,7100 g/mol

TPSA

26,00 Ų

المجالات العلاجية

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

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SMILES

Cl.NC12CC3CC(CC(C3)C1)C2

InChI

InChI=1S/C10H17N.ClH/c11-10-4-7-1-8(5-10)3-9(2-7)6-10;/h7-9H,1-6,11H2;1H

Molecular Formula

C10H18ClN

HBD / HBA

2 / 1

الروابط القابلة للدوران

0

الذرات الثقيلة

12

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

The hydrochloride salt form of amantadine, providing the same antiviral activity against influenza A and dopaminergic effects useful in Parkinson's disease and drug-induced movement disorders. This commonly used salt form is well-absorbed orally and excreted unchanged by the kidneys, requiring dose adjustment in patients with reduced kidney function.

Yes, Amantadine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1569. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 64150. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.