Auranofin

CHEMBL1366 Phase 4 معتمد Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

678.5 g/mol

LogP

—

Phase

4

An oral gold-containing compound originally developed for rheumatoid arthritis that reduces joint inflammation by modulating immune cell activity. It is now being investigated for its ability to induce oxidative stress in cancer cells and inhibit certain pathogens including HIV.

الوزن الجزيئي

678,5000 g/mol

TPSA

115,00 Å²

المجالات العلاجية

Pain Management Non-Small Cell Lung Cancer Lymphoma Chronic Pain HIV/AIDS Tuberculosis Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

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SMILES

CCP(CC)CC.CC(=O)OC[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)[S-])OC(=O)C)OC(=O)C)OC(=O)C.[Au+]

InChI

InChI=1S/C14H20O9S.C6H15P.Au/c1-6(15)19-5-10-11(20-7(2)16)12(21-8(3)17)13(14(24)23-10)22-9(4)18;1-4-7(5-2)6-3;/h10-14,24H,5H2,1-4H3;4-6H2,1-3H3;/q;;+1/p-1/t10-,11-,12+,13-,14+;;/m1../s1

Molecular Formula

C20H34AuO9PS

HBD / HBA

- / 10

الروابط القابلة للدوران

12

الذرات الثقيلة

32

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

An oral gold-containing compound originally developed for rheumatoid arthritis that reduces joint inflammation by modulating immune cell activity. It is now being investigated for its ability to induce oxidative stress in cancer cells and inhibit certain pathogens including HIV.

Yes, Auranofin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1366. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 16667669. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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البنية

بيانات سريعة

الصيغة الجزيئية: C20H34AuO9PS
المرادفات: 1

روابط خارجية

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إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.