Benfluorex

CHEMBL400599 Phase 4 معتمد Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

351.4 g/mol

LogP

4.6

Phase

4

A fenfluramine derivative that was used to improve glucose tolerance and lower triglycerides in type 2 diabetes, but it was withdrawn globally due to a risk of serious heart valve abnormalities.

الوزن الجزيئي

351,4000 g/mol

LogP

4,60

TPSA

38,30 Å²

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Type 2 Diabetes

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

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SMILES

CC(Cc1cccc(C(F)(F)F)c1)NCCOC(=O)c1ccccc1

InChI

InChI=1S/C19H20F3NO2/c1-14(12-15-6-5-9-17(13-15)19(20,21)22)23-10-11-25-18(24)16-7-3-2-4-8-16/h2-9,13-14,23H,10-12H2,1H3

Molecular Formula

C19H20F3NO2

HBD / HBA

1 / 6

الروابط القابلة للدوران

8

الذرات الثقيلة

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

A fenfluramine derivative that was used to improve glucose tolerance and lower triglycerides in type 2 diabetes, but it was withdrawn globally due to a risk of serious heart valve abnormalities.

Yes, Benfluorex is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL400599. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 2318. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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البنية

بيانات سريعة

الصيغة الجزيئية: C19H20F3NO2

روابط خارجية

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إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.