Berberine

CHEMBL295124 Phase 4 معتمد Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
336.4 g/mol
LogP
3.6
Phase
4

A plant-derived alkaloid found in several herbs, with evidence suggesting benefits for blood sugar control, cholesterol levels, and gut health. It activates a key enzyme involved in energy metabolism, similar in some ways to metformin. It is used as a dietary supplement and in traditional medicine.

الوزن الجزيئي

336,4000 g/mol

LogP

3,60

TPSA

40,80 Ų

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

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SMILES

COc1ccc2cc3[n+](cc2c1OC)CCc1cc2c(cc1-3)OCO2

InChI

InChI=1S/C20H18NO4/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2/h3-4,7-10H,5-6,11H2,1-2H3/q+1

Molecular Formula

C20H18NO4+

HBD / HBA

- / 4

الروابط القابلة للدوران

2

الذرات الثقيلة

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

A plant-derived alkaloid found in several herbs, with evidence suggesting benefits for blood sugar control, cholesterol levels, and gut health. It activates a key enzyme involved in energy metabolism, similar in some ways to metformin. It is used as a dietary supplement and in traditional medicine.

Yes, Berberine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL295124. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 2353. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.