Betamethasone Acetate
The acetate ester form of betamethasone, a corticosteroid often given by injection in combination with betamethasone sodium phosphate for a longer-lasting anti-inflammatory effect. It is used to treat joint inflammation, skin conditions, and allergic reactions. The depot effect allows sustained release at the injection site.
الوزن الجزيئي
434,5000 g/mol
LogP
2,80
TPSA
101,00 Ų
قاعدة ليبينسكي للخمسة
ناجح
المجالات العلاجية
آلية العمل
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
البنية ثنائية الأبعاد
Cite this structure
Embed this structure
SMILES
CC(=O)OCC(=O)[C@@]1(O)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
InChI
InChI=1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17-,18-,19-,21-,22-,23-,24-/m0/s1
Molecular Formula
C24H31FO6
HBD / HBA
2 / 7
الروابط القابلة للدوران
4
الذرات الثقيلة
31
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
The acetate ester form of betamethasone, a corticosteroid often given by injection in combination with betamethasone sodium phosphate for a longer-lasting anti-inflammatory effect. It is used to treat joint inflammation, skin conditions, and allergic reactions. The depot effect allows sustained release at the injection site.
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Yes, Betamethasone Acetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200538. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 443967. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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