Brolucizumab
A single-chain antibody fragment that inhibits vascular endothelial growth factor A, used by injection into the eye to treat wet age-related macular degeneration and diabetic macular edema. Its small molecular size may allow for greater tissue penetration and potentially longer intervals between injections compared to some other anti-VEGF agents. Rare but serious cases of retinal vasculitis have been reported.
المجالات العلاجية
آلية العمل
As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.
HBD / HBA
- / -
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
A single-chain antibody fragment that inhibits vascular endothelial growth factor A, used by injection into the eye to treat wet age-related macular degeneration and diabetic macular edema. Its small molecular size may allow for greater tissue penetration and potentially longer intervals between injections compared to some other anti-VEGF agents. Rare but serious cases of retinal vasculitis have been reported.
As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.
Yes, Brolucizumab is an approved drug. It has reached clinical phase 4. It is classified as a Antibody.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3707357. Open-access bioactivity database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.
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