Carmustine
An alkylating chemotherapy agent belonging to the nitrosourea class that works by crosslinking DNA and disrupting RNA synthesis, killing rapidly dividing cancer cells. It is used to treat brain tumors, multiple myeloma, Hodgkin's and non-Hodgkin's lymphomas. Significant bone marrow suppression and pulmonary toxicity are important concerns during therapy.
الوزن الجزيئي
214,0500 g/mol
LogP
1,50
TPSA
61,80 Ų
قاعدة ليبينسكي للخمسة
ناجح
المجالات العلاجية
Pharmacokinetics (PK)
Pharmacodynamics (PD)
البنية ثنائية الأبعاد
Cite this structure
Embed this structure
SMILES
O=NN(CCCl)C(=O)NCCCl
InChI
InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)
Molecular Formula
C5H9Cl2N3O2
HBD / HBA
1 / 3
الروابط القابلة للدوران
4
الذرات الثقيلة
12
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
An alkylating chemotherapy agent belonging to the nitrosourea class that works by crosslinking DNA and disrupting RNA synthesis, killing rapidly dividing cancer cells. It is used to treat brain tumors, multiple myeloma, Hodgkin's and non-Hodgkin's lymphomas. Significant bone marrow suppression and pulmonary toxicity are important concerns during therapy.
Yes, Carmustine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL513. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2578. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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