Ceftriaxone Sodium
The sodium salt preparation of ceftriaxone is the standard formulation used in clinical practice for intravenous or intramuscular injection. It shares all the pharmacological properties and indications of the parent compound, including once-daily dosing convenience. Special caution is required in neonates due to the risk of biliary sludge and interactions with calcium-containing infusion fluids.
الوزن الجزيئي
598,6000 g/mol
TPSA
280,00 Ų
المجالات العلاجية
Pharmacokinetics (PK)
Pharmacodynamics (PD)
البنية ثنائية الأبعاد
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SMILES
CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(CSc3nc(=O)c([O-])nn3C)CS[C@H]12)c1csc(N)n1.CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(CSc3nc(=O)c([O-])nn3C)CS[C@H]12)c1csc(N)n1.O.O.O.O.O.O.O.[Na+].[Na+].[Na+].[Na+]
InChI
InChI=1S/2C18H18N8O7S3.4Na.7H2O/c2*1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7;;;;;;;;;;;/h2*5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32);;;;;7*1H2/q;;4*+1;;;;;;;/p-4/b2*24-8-;;;;;;;;;;;/t2*9-,15-;;;;;;;;;;;/m11.........../s1
Molecular Formula
C18H16N8Na2O7S3
HBD / HBA
2 / 14
الروابط القابلة للدوران
8
الذرات الثقيلة
38
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
The sodium salt preparation of ceftriaxone is the standard formulation used in clinical practice for intravenous or intramuscular injection. It shares all the pharmacological properties and indications of the parent compound, including once-daily dosing convenience. Special caution is required in neonates due to the risk of biliary sludge and interactions with calcium-containing infusion fluids.
Yes, Ceftriaxone Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6067656. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 23715082. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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