Chloroquine Hydrochloride

CHEMBL4297165 Phase 4 معتمد Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
392.8 g/mol
LogP
Phase
4

The hydrochloride salt of chloroquine is used parenterally for severe or complicated malaria when oral administration is not possible. It carries the same risks of cardiac arrhythmias and retinal toxicity as the oral formulations. Careful dosing and cardiac monitoring are essential during parenteral administration.

الوزن الجزيئي

392,8000 g/mol

TPSA

28,20 Ų

المجالات العلاجية

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

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SMILES

CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12.Cl.Cl

InChI

InChI=1S/C18H26ClN3.2ClH/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;;/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*1H

Molecular Formula

C18H28Cl3N3

HBD / HBA

3 / 3

الروابط القابلة للدوران

8

الذرات الثقيلة

24

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

The hydrochloride salt of chloroquine is used parenterally for severe or complicated malaria when oral administration is not possible. It carries the same risks of cardiac arrhythmias and retinal toxicity as the oral formulations. Careful dosing and cardiac monitoring are essential during parenteral administration.

Yes, Chloroquine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4297165. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 83820. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.