Chloroquine Phosphate

CHEMBL58510 Phase 4 معتمد Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

515.9 g/mol

LogP

—

Phase

4

The phosphate salt is the most commonly dispensed oral form of chloroquine, used for malaria prevention and treatment as well as long-term management of lupus and rheumatoid arthritis. It is generally well tolerated for short-term use, though GI upset is common. Ophthalmological surveillance is mandatory for patients on long-term therapy due to cumulative retinal toxicity.

الوزن الجزيئي

515,9000 g/mol

TPSA

184,00 Å²

المجالات العلاجية

Infectious Disease Melanoma Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Age-Related Macular Degeneration Respiratory Disease Non-Small Cell Lung Cancer Rheumatoid Arthritis Chronic Obstructive Pulmonary Disease Migraine Generalized Anxiety Disorder Psoriasis Systemic Lupus Erythematosus Multiple Sclerosis Chronic Kidney Disease Obesity Transplant Medicine Type 2 Diabetes Hypertension Breast Cancer Atopic Dermatitis Malaria HIV/AIDS Hepatitis C Tuberculosis Atrial Fibrillation Cardiovascular Disease Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

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SMILES

CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12.O=P(O)(O)O.O=P(O)(O)O

InChI

InChI=1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4)

Molecular Formula

C18H32ClN3O8P2

HBD / HBA

7 / 11

الروابط القابلة للدوران

8

الذرات الثقيلة

32

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

The phosphate salt is the most commonly dispensed oral form of chloroquine, used for malaria prevention and treatment as well as long-term management of lupus and rheumatoid arthritis. It is generally well tolerated for short-term use, though GI upset is common. Ophthalmological surveillance is mandatory for patients on long-term therapy due to cumulative retinal toxicity.

Yes, Chloroquine Phosphate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL58510. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 64927. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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البنية

بيانات سريعة

الصيغة الجزيئية: C18H32ClN3O8P2

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إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.