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Cholic Acid

CHEMBL205596 Phase 4 معتمد Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
408.6 g/mol
LogP
3.6
Phase
4

A primary bile acid that facilitates the absorption of dietary fats and fat-soluble vitamins in the small intestine by emulsifying lipid droplets. It is used therapeutically to treat inborn errors of bile acid synthesis, rare metabolic disorders that impair the body's ability to produce bile acids naturally. Oral replacement with cholic acid helps restore normal bile flow and prevents progressive liver damage.

الوزن الجزيئي

408,6000 g/mol

LogP

3,60

TPSA

98,00 Ų

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Rheumatoid Arthritis Gastroesophageal Reflux Disease Non-Alcoholic Fatty Liver Disease Hyperlipidemia Obesity Type 2 Diabetes Breast Cancer Atopic Dermatitis HIV/AIDS Hepatitis C Heart Failure Cardiovascular Disease Colorectal Cancer Leukemia

آلية العمل

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

البنية ثنائية الأبعاد

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

                

                

                
                

                    
InChI

                    
InChI=1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C24H40O5

                    

                    
                    

                        
HBD / HBA

                        
4 / 5

                    

                    
                    

                        
الروابط القابلة للدوران

                        
4

                    

                    
                    
                    

                        
الذرات الثقيلة

                        
29

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
الأسئلة الشائعة

                

                    
                    

                        
                        

                            
A primary bile acid that facilitates the absorption of dietary fats and fat-soluble vitamins in the small intestine by emulsifying lipid droplets. It is used therapeutically to treat inborn errors of bile acid synthesis, rare metabolic disorders that impair the body's ability to produce bile acids naturally. Oral replacement with cholic acid helps restore normal bile flow and prevents progressive liver damage.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Cholic Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL205596.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 221493.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
إخلاء المسؤولية الطبية

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.