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Clioquinol

CHEMBL497 Phase 4 معتمد Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
305.5 g/mol
LogP
3.5
Phase
4

A halogenated hydroxyquinoline with both antifungal and antibacterial properties once widely used for skin infections and traveler's diarrhea. Its systemic use was largely abandoned after links to subacute myelo-optic neuropathy, though topical application remains in some formulations.

الوزن الجزيئي

305,5000 g/mol

LogP

3,50

TPSA

33,10 Ų

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Epilepsy Psoriasis Lymphoma Leukemia

آلية العمل

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

البنية ثنائية الأبعاد

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Oc1c(I)cc(Cl)c2cccnc12

                

                

                
                

                    
InChI

                    
InChI=1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H

                

                

                

                    
                    

                        
Molecular Formula

                        
C9H5ClINO

                    

                    
                    

                        
HBD / HBA

                        
1 / 2

                    

                    
                    

                        
الروابط القابلة للدوران

                        
0

                    

                    
                    
                    

                        
الذرات الثقيلة

                        
13

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
الأسئلة الشائعة

                

                    
                    

                        
                        

                            
A halogenated hydroxyquinoline with both antifungal and antibacterial properties once widely used for skin infections and traveler's diarrhea. Its systemic use was largely abandoned after links to subacute myelo-optic neuropathy, though topical application remains in some formulations.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Clioquinol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL497.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2788.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
إخلاء المسؤولية الطبية

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.