Cobicistat

CHEMBL2095208 Phase 4 معتمد Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

776.0 g/mol

LogP

5.7

Phase

4

A pharmacokinetic enhancer that inhibits CYP3A enzymes to boost blood levels of co-administered antiretroviral drugs without having intrinsic antiviral activity itself. It is used in combination HIV regimens as a booster, similar in function to ritonavir.

الوزن الجزيئي

776,0000 g/mol

LogP

5,70

TPSA

195,00 Å²

قاعدة ليبينسكي للخمسة

راسب

المجالات العلاجية

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Generalized Anxiety Disorder Insomnia Obesity Hypertension Breast Cancer Malaria HIV/AIDS Hepatitis C Tuberculosis Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

SVG PNG

Cite this structure

Embed this structure

SMILES

CC(C)c1nc(CN(C)C(=O)N[C@@H](CCN2CCOCC2)C(=O)N[C@H](CC[C@H](Cc2ccccc2)NC(=O)OCc2cncs2)Cc2ccccc2)cs1

InChI

InChI=1S/C40H53N7O5S2/c1-29(2)38-43-34(27-53-38)25-46(3)39(49)45-36(16-17-47-18-20-51-21-19-47)37(48)42-32(22-30-10-6-4-7-11-30)14-15-33(23-31-12-8-5-9-13-31)44-40(50)52-26-35-24-41-28-54-35/h4-13,24,27-29,32-33,36H,14-23,25-26H2,1-3H3,(H,42,48)(H,44,50)(H,45,49)/t32-,33-,36+/m1/s1

Molecular Formula

C40H53N7O5S2

HBD / HBA

3 / 10

الروابط القابلة للدوران

20

الذرات الثقيلة

54

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

A pharmacokinetic enhancer that inhibits CYP3A enzymes to boost blood levels of co-administered antiretroviral drugs without having intrinsic antiviral activity itself. It is used in combination HIV regimens as a booster, similar in function to ritonavir.

Yes, Cobicistat is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2095208. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 25151504. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

هل تبحث عن معلومات ملائمة للمرضى؟

Cobicistat على PillFYI

البنية

بيانات سريعة

الصيغة الجزيئية: C40H53N7O5S2
المرادفات: 6

روابط خارجية

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.