Cravacitinib

CHEMBL4596392 Phase 4 معتمد Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

422.4 g/mol

LogP

1.2

Phase

4

A targeted therapy being investigated as a treatment for inflammatory skin conditions, particularly atopic dermatitis. It works by inhibiting specific enzymes involved in the immune response that drives skin inflammation.

الوزن الجزيئي

422,4000 g/mol

LogP

1,20

TPSA

136,00 Å²

قاعدة ليبينسكي للخمسة

ناجح

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

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SMILES

CNC(=O)c1nnc(NC(=O)C2CC2)cc1Nc1cccc(-c2ncn(C)n2)c1OC

InChI

InChI=1S/C20H22N8O3/c1-21-20(30)16-14(9-15(25-26-16)24-19(29)11-7-8-11)23-13-6-4-5-12(17(13)31-3)18-22-10-28(2)27-18/h4-6,9-11H,7-8H2,1-3H3,(H,21,30)(H2,23,24,25,29)

Molecular Formula

C20H22N8O3

HBD / HBA

3 / 8

الروابط القابلة للدوران

7

الذرات الثقيلة

31

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

A targeted therapy being investigated as a treatment for inflammatory skin conditions, particularly atopic dermatitis. It works by inhibiting specific enzymes involved in the immune response that drives skin inflammation.

Yes, Cravacitinib is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4596392. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 138713709. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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البنية

بيانات سريعة

الصيغة الجزيئية: C20H22N8O3

روابط خارجية

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إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.