Dacomitinib Anhydrous

CHEMBL2110732 Phase 4 معتمد Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

469.9 g/mol

LogP

4.4

Phase

4

An anhydrous form of dacomitinib, an EGFR inhibitor used to treat non-small cell lung cancer with activating EGFR mutations. It blocks signaling pathways that drive cancer cell proliferation.

الوزن الجزيئي

469,9000 g/mol

LogP

4,40

TPSA

79,40 Å²

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Pancreatic Cancer Lymphoma Breast Cancer Prostate Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

SVG PNG

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SMILES

COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)/C=C/CN1CCCCC1

InChI

InChI=1S/C24H25ClFN5O2/c1-33-22-14-20-17(24(28-15-27-20)29-16-7-8-19(26)18(25)12-16)13-21(22)30-23(32)6-5-11-31-9-3-2-4-10-31/h5-8,12-15H,2-4,9-11H2,1H3,(H,30,32)(H,27,28,29)/b6-5+

Molecular Formula

C24H25ClFN5O2

HBD / HBA

2 / 7

الروابط القابلة للدوران

7

الذرات الثقيلة

33

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

An anhydrous form of dacomitinib, an EGFR inhibitor used to treat non-small cell lung cancer with activating EGFR mutations. It blocks signaling pathways that drive cancer cell proliferation.

Yes, Dacomitinib Anhydrous is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2110732. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 11511120. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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البنية

بيانات سريعة

الصيغة الجزيئية: C24H25ClFN5O2

روابط خارجية

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إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.