Dicyclomine Hydrochloride

CHEMBL1200479 Phase 4 معتمد Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
345.9 g/mol
LogP
Phase
4

The hydrochloride salt of dicyclomine, used in oral and injectable preparations to relieve intestinal spasms and treat irritable bowel syndrome. It blocks muscarinic acetylcholine receptors in the gut smooth muscle to reduce cramping. Anticholinergic side effects such as dry mouth and constipation are common.

الوزن الجزيئي

345,9000 g/mol

TPSA

29,50 Ų

آلية العمل

Increases water content in the intestinal lumen through osmotic or stimulant mechanisms, promoting bowel motility and facilitating defecation.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Increases water content in the intestinal lumen through osmotic or stimulant mechanisms, promoting bowel motility and facilitating defecation.

البنية ثنائية الأبعاد

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SMILES

CCN(CC)CCOC(=O)C1(C2CCCCC2)CCCCC1.Cl

InChI

InChI=1S/C19H35NO2.ClH/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17;/h17H,3-16H2,1-2H3;1H

Molecular Formula

C19H36ClNO2

HBD / HBA

1 / 3

الروابط القابلة للدوران

8

الذرات الثقيلة

23

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

The hydrochloride salt of dicyclomine, used in oral and injectable preparations to relieve intestinal spasms and treat irritable bowel syndrome. It blocks muscarinic acetylcholine receptors in the gut smooth muscle to reduce cramping. Anticholinergic side effects such as dry mouth and constipation are common.

Increases water content in the intestinal lumen through osmotic or stimulant mechanisms, promoting bowel motility and facilitating defecation.

Yes, Dicyclomine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200479. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 441344. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.